含乌头碱类的植物种类较多，如草乌、附子等，因具有药用价值,民间常用含乌头碱类的植物浸泡药酒，用于治疗风湿性关节痛等疾病。但在使用过程中如对剂量把握不规范或直接用未加工的原材料浸泡药酒，人在饮用后，易导致乌头碱中毒，严重的甚至危及生命。而目前有关乌头碱中毒的资料和文献中，大多仅有口服中毒量和致死量的数值范围，尚未见统一的中毒和致死血液浓度的数值范围。本文报道一例乌头碱中毒案例及其致死血浓度数值供参考。

关键字：中毒；乌头碱中毒；法医学鉴定

Abstract：

There are many kinds of plants containing aconitine, such as aconitine, Aconite, etc. Because of their medicinal value, plant soaking medicinal wine containing aconitine is commonly used for the treatment of rheumatic arthralgia and other diseases. However, if the dosage is not standardized or the medicinal liquor is soaked in raw materials, aconitine poisoning can easily occur after drinking, which may even be life-threatening. However, in the current literature on aconitine poisoning, most of them only have the value range of oral poisoning dose and lethal dose, and there is no uniform value range of poisoning and lethal blood concentration. This paper reports a case of aconitine poisoning and its lethal blood concentration for reference

Keywords: Poisoning; Aconitine poisoning; Forensic identification

正文内容 / Content：

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参考文献 / References：

张伟, 李芳, 刘志文, 等. 急性乌头碱中毒致心律失常的治疗方法应用进展[J]. 山东医药, 2022, 62(12): 91-94.
干金文, 金刚, 成广海, 等. 成功救治乌头碱中毒致心律失常的分析[J]. 转化医学电子杂志, 2017, 4(11): 58-61.
蒋小花, 何柳平, 杨仕福, 等. 急性乌头碱中毒致心律失常36例临床分析[J]. 蛇志, 2017, 29(1): 102-103.
李建强. 乌头碱中毒致心律失常56例临床分析[J]. 当代医学, 2016, 22(2): 40-41.
何益平, 郭航远, 裘宇芳, 等. 乌头碱中毒致心律失常19例临床分析[J]. 岭南心血管病杂志, 2014, 20(2): 155-157.
张阳, 沈丽娟, 殷兆芳, 等. 乌头碱中毒致心律失常60例临床研究[J]. 中国医药导刊, 2012, 14(2): 2.
田野, 潘德田, 刘会勇. 乌头碱中毒致心律失常30例[J]. 临床内科杂志, 2013， 30(2): 133-134.
李朝晖. 有毒植物中毒[M]//刘良主编, 法医毒理学. 第五版, 北京：人民卫生出版社，2016： 184-187.
郑冬律. 急性乌头碱中毒死亡1例[J]. 中国法医学杂志, 2018, 33(6): 651,654.
Beike J，Frommherz L，Wood M, et al. Determination of aconitine in body fluids by LC-MS-MS[J]. International Journal of Legal Medicine, 2004, 118(5): 289-293.