摘 要：
目的:分析活动性结核病母亲所生新生儿的临床管理经验及中期随访结局。方法：回顾性分析我院2023-2025年收治的3例活动性结核病母亲所生新生儿的临床资料。母亲不同孕周启动规范抗结核治疗。新生儿出生后均接受了包括临床症状评估、结核菌素皮肤试验（TST）、γ-干扰素释放试验（IGRA）以及胸部影像学在内的结核病相关检查，同时进行随访。结果：3例新生儿中，2例足月，1例早产（26周+）。所有新生儿出生时评估均未发现活动性结核以及结核潜伏感染的证据。在规范随访下，2例完成至少2年随访，均生长发育良好，未发生活动性结核病。结论：对于孕期接受规范治疗的结核病母亲所生新生儿，通过出生后及时、系统的评估和规范随访，可以实现良好的中期结局。多学科协作和长期随访至关重要。
关键词：活动性结核 ；妊娠；母亲；新生儿
Abstract:
Objective: Analysis of clinical management experience and mid-term follow-up outcome of newborns born to active tuberculosis mothers.Method: The clinical data of 3 newborns born to mothers with active tuberculosis from 2023-2025 in our hospital were retrospectively analyzed. Mothers initiate standardized anti tuberculosis treatment at different gestational weeks. After birth, all newborns received tuberculosis related examinations, including clinical symptom assessment, tuberculin skin test (TST), gamma interferon release test (IGRA) and chest imaging, and were followed up.Result: Among the 3 newborns, 2 were full-term and 1 was premature (26 weeks+). No evidence of active tuberculosis or latent tuberculosis infection was found in all newborn assessments at birth. Under the standard follow-up, 2 cases completed at least 2 years of follow-up, and all grew well without active tuberculosis.Conclusion: For newborns born to tuberculosis mothers who received standardized treatment during pregnancy, good mid-term outcomes can be achieved through timely and systematic evaluation and standardized follow-up after birth. Multidisciplinary collaboration and long-term follow-up are crucial.
Keywords: Active tuberculosis; Pregnancy; Mother; Newborn
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