IgA血管炎旧称过敏性紫癜，是儿科常见一种全身性的小血管炎，发病机制不清，临床诊断中没有特异性的检验指标，主要靠临床诊断：可触性皮疹加上任何部位活检提示IgA的沉积。但在实际临床工作中，典型皮疹只占本病的一部分，绝大部分病例无皮疹，活检在临床上可操作性差，因此，这些并不特异的临床表现难以同其它疾病鉴别，也给IgAV的临床诊断标准提出了挑战！目前为止，仍没有关于IgAV的特异的早期实验检查指标，本文将近些年来的研究进展进行综述。

关键字：IgA血管炎；过敏性紫癜；标志物；早期诊断，儿童

Abstract：

IgA vasculitis, formerly known as anaphylactoid purpura, is a common systemic small vasculitis in pediatrics, the pathogenesis is unclear, there is no specific test indicators in clinical diagnosis, mainly rely on clinical diagnosis: palpable rash coupled with any part of the biopsy to suggest IgA deposition. However, in actual clinical work, typical rash only accounts for a part of the disease, the vast majority of cases have no rash, and the biopsy is poor in clinical operability. Therefore, these non-specific clinical manifestations are difficult to distinguish from other diseases, and also pose challenges to the clinical diagnostic criteria of IgAV! Up to now, there are no specific early test indicators for IgAV. This article reviews the research progress in recent years.

Keywords: IgA vasculitis; Anaphylactoid purpura; Markers; Early diagnosis, children

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